Gender Disparities in Hematological and Renal Markers in End-Stage Renal Disease Prior to Kidney Transplantation: A Retrospective Multicenter Study from the Kurdistan Region of Iraq

Authors

DOI:

https://doi.org/10.23918/eajse.v11i3p9

Keywords:

Creatinine, End-stage Renal Disease, Gender Differences, Hematological Markers, Kidney Transplantation

Abstract

End-stage renal disease (ESRD) is a crucial public health challenge, especially in regions with limited data on gender-based clinical characteristics before kidney transplantation (KT).  This study aims to examine gender-related differences in hematological and renal parameters among ESRD before KT in the Kurdistan Region of Iraq. Clinical information of 200 ESRD individuals, including 105 males and 95 females, aged from 18 to 65, was reviewed over a period of three years across three large hospitals between 2018 and 2024. The data comprised kidney function, electrolytes, CBC, and thyroid hormones. Except for MCH (mean corpuscular hemoglobin), no biochemical or hematological derived parameter differed significantly between gender significant lower value in female 27.37 ± 0.58 pg, compared to males, 28.50 ± 0.25 pg, p- value = 0.037. Urea, PCT, MPV, and PLT were found to be independent predictors of serum creatinine as shown by the regression analysis. In conclusion, gender-specific pre-transplant laboratory differences in ESRD were modest in extent, yet clinically significant for the female lower MCH that might defer KT eligibility due to under-recognized renal anemia. In addition, platelet-based indices mirroring inflammatory-hemodynamic processes are also associated with serum creatinine. These results lay the groundwork for more gender-informed, ethically sound, and model-refined KT readiness measures.

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Published

2026-02-01

Issue

Vol. 11 No. 3 (2025)

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Articles

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Copyright (c) 2026 Zhikal Khudhur, Shnyar Qadir, Yara O. Khudhir, Helin A. Haji, Kale Q. Sayid

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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Eurasian J. Sci. Eng is distributed under the terms of the Creative Commons Attribution License 4.0 (CC BY-4.0) https://creativecommons.org/licenses/by/4.0/

How to Cite

Khudhur, Z., Qadir, S., Khudhir, Y., Haji, H., & Sayid, K. (2026). Gender Disparities in Hematological and Renal Markers in End-Stage Renal Disease Prior to Kidney Transplantation: A Retrospective Multicenter Study from the Kurdistan Region of Iraq. EURASIAN JOURNAL OF SCIENCE AND ENGINEERING, 11(3), 136-148. https://doi.org/10.23918/eajse.v11i3p9

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