1. Home
  2. 2024-V10-I2
  3. Biological Activity and Taxonomy of Persea americana Mill: A Systematic Review
Statistics

Article Views: 71

PDF Downloads: 14

  • Date of Publication : 2024-05-02 Article Type : Research Article
  • Biological Activity and Taxonomy of Persea americana Mill: A Systematic Review

    Abdulrahman Mahmoud Dogara * ¹

    Affiliation

    ¹ Biology Education Department, Tishk International University, Erbil, Iraq    
    *Corresponding Author


    ORCID :

    Abdulrahman Mahmoud Dogara: https://orcid.org/0000-0003-0944-7282


    DOI :

    https://doi.org/10.23918/eajse.v10i2p04


    Article History

    Received: 2024-01-16

    Revised: 2024-03-20

    Accepted: 2024-04-07

    Abstract

    Medicinal plants are the main raw materials utilized in the manufacture of pharmaceutical products around the world. Avocado (Persea americana Mill.) is a high-nutrient tropical fruit of the Lauraceae family. The study provides a concise summary of the most important results from the many studies conducted on P. americana since 2010 that have sought to identify active principles found in the plant that can treat human ailments. To find published articles, searches were conducted through Google Scholar, PubMed, ScienceDirect, Web of Science, BioMed Central, Science, Scopus, and Springer.  In the 113 articles published, it was discovered that the plant extract worked well against cancer, free radicals, bacteria, parasites, inflammation, and diabetes. The chemical compound that was mentioned the most frequently was polyphenol. Clinical studies involving humans are necessary to confirm and improve the effectiveness of avocado seed, peel, and leaf extracts in the treatment of diseases. Although the safety of avocado extract has been shown in animal models, it is imperative to evaluate the dosage and potential adverse effects in humans before deeming it an effective and safe treatment. The extract of P. americana may have a significant impact on the advancement of nutraceuticals.

    Keywords :

    Antioxidants; Anticancer; Avocado; Antimicrobial


    [1]    Calderón-Oliver, M., H.B. Escalona-Buendía, O.N. Medina-Campos, J. Pedraza-Chaverri, R. Pedroza-Islas& E. Ponce-Alquicira, Optimization of the antioxidant and antimicrobial response of the combined effect of nisin and avocado byproducts. LWT-Food Science and Technology. 2016, 65:  46-52. https://doi.org/10.1016/j.lwt.2015.07.048.

    Google Scholar 
    [2]    Kupnik, K., M. Primožič, V. Kokol, Ž. Knez& M. Leitge E. Enzymatic, Antioxidant, and Antimicrobial Activities of Bioactive Compounds from Avocado (Persea americana L.) Seeds. Plants. 2023, 12(5):  1201. https://doi.org/10.3390/plants12051201


    [3]    Dabas, D., R.J. Elias, G.R. Ziegler& Lambert, J.D. In vitro antioxidant and cancer inhibitory activity of a colored avocado seed extract. International Journal of Food Science. 2019. https://doi.org/10.1155/2019/6509421

    Google Scholar 
    [4]    Tan, C.X., R. Chin, S.T. Tan & Tan, S.S. Phytochemicals and antioxidant activity of ultrasound-assisted avocado seed extract. Malaysian Journal of Analytical Sciences. 2022, 26:  439-446.

    Google Scholar 
    [5]    Yasir, M., S. Das & Kharya, M.  The phytochemical and pharmacological profile of Persea americana Mill. Pharmacognosy reviews. 2010, 4(7):  77-84. https://doi.org/10.4103/0973-7847.65332

    Google Scholar 
    [6]    Ranade, S.S. & Thiagarajan, P. A review on Persea Americana Mill. (Avocado)-Its fruit and oil. International Journal of PharmTech Research. 2015, 8(6):  72-77.

    Google Scholar 
    [7]    Ochoa-Zarzosa, A., M. Baez-Magana, J.J. Guzman-Rodriguez, L.J. Flores-Alvarez, M. Lara-Márquez, B. Zavala-Guerrero, R. Salgado-Garciglia, R. Lopez-Gomez& López-Meza, J.E. Bioactive molecules from native Mexican avocado fruit (Persea americana var. drymifolia): a review. Plant Foods for Human Nutrition. 2021, 76:  133-142. https://doi.org/10.1007/s11130-021-00887-7

    Google Scholar 
    [8]    Ashande, C.M., G.L. Lufuluabo, J. Mukiza& P.T. Mpiana, A mini-review on the Phytochemistry and Pharmacology of the medicinal plant species Persea americana Mill. (Lauraceae). Discovery Phytomedicine. 2019, 6(3):  102-111. https://doi.org/10.15562/phytomedicine.2019.99

    Google Scholar 
    [9]    Abdulrahman, M.D., A.M. Zakariya, H.A. Hama, S.W. Hamad, S.S. Al-Rawi, S.W. Bradosty& Ibrahim, A.H. Ethnopharmacology, biological evaluation, and chemical composition of Ziziphus spina-christi (L.) Desf.: A Review. Advances in Pharmacological and Pharmaceutical Sciences. 2022. https://doi.org/10.1155/2022/4495688

    Google Scholar 
    [10]    Dogara, A.M., A systematic review on the biological evaluation of Calotropis procera (Aiton) Dryand. Future Journal of Pharmaceutical Sciences. 2023, 9(1):  1-16. https://doi.org/10.1186/s43094-023-00467-3.  

    Google Scholar 
    [11]    Dogara, A.M. Biological activity and chemical composition of Detarium microcarpum Guill. and Perr—a systematic review. Advances in Pharmacological and Pharmaceutical Sciences. 2022, 2022. https://doi.org/10.1155/2022/7219401

    Google Scholar 
    [12]    Rodríguez-Carpena, J.-G., D. Morcuende, M.-J. Andrade, P. Kylli & Estévez, A.M (Persea americana Mill.) phenolics, in vitro antioxidant and antimicrobial activities, and inhibition of lipid and protein oxidation in porcine patties. Journal of agricultural and food chemistry. 2011, 59(10):  5625-5635.

    Google Scholar 
    [13]    Castro-López, C., I. Bautista-Hernández, M.D. González-Hernández, G.C. Martínez-Ávila, R. Rojas, A. Gutiérrez-Díez, N. Medina-Herrera & Aguirre-Arzola,V.E. Polyphenolic profile and antioxidant activity of leaf purified hydroalcoholic extracts from seven Mexican Persea americana cultivars. Molecules. 2019, 24(1):  173. https://doi.org/10.3390/molecules24010173

    Google Scholar 
    [14]    Rahman, N., S.M. Sabang, R. Abdullah & Bohari,B. Antioxidant properties of the methanolic extract of avocado fruit peel (Persea americana Mill.) from Indonesia. Journal of Advanced Pharmaceutical Technology & Research. 2022, 13(3):  166. https://doi.org/10.4103/japtr.japtr_22_22.

    Google Scholar 
    [15]    Skenderidis, P., S. Leontopoulos, K. Petrotos,  Mitsagga C & Giavasis, L.The in vitro and in vivo synergistic antimicrobial activity assessment of Vacuum Microwave Assisted aqueous extracts from pomegranate and avocado fruit peels and avocado seeds based on a mixtures design model. Plants. 2021, 10(9):  1757. https://doi.org/10.3390/plants10091757

    Google Scholar 
    [16]    Kamaraj, M., V. Dhana Rangesh Kumar, Nithya, T.  & U. Danya, U.  Assessment of antioxidant, antibacterial activity and phytoactive compounds of aqueous extracts of avocado fruit peel from Ethiopia. International Journal of Peptide Research and Therapeutics. 2020, 26:  1549-1557. https://doi.org/10.1007/s10989-019-09965-6

    Google Scholar 
    [17]    Soledad, C.P.T., H.C. Paola, O.-V.C. Enrique, R.-L.I. Israel, N.-M. GuadalupeVirginia& Raúl, Á.S. Avocado seeds (Persea americana cv. Criollo sp.): Lipophilic compounds profile and biological activities. Saudi journal of biological sciences. 2021, 28(6):  3384-3390. https://doi.org/10.1016/j.sjbs.2021.02.087

    Google Scholar 

    [18]    Sudhasupriya, P., A.S. Begam& Rajeshkumar, S. Screening for antioxidant and antimicrobial activity of seed extracts of avocado pear. Research Journal of Pharmacy and Technology. 2017, 10(6):  1991-1996. https://doi.org/10.5958/0974-360X.2017.00348.1

    Google Scholar 
    [19]    Razola-Díaz, M.d.C., S. De Montijo-Prieto, M.J. Aznar-Ramos, M. Jiménez-Valera, A. Ruiz-Bravo, V. Verardo& Gómez-Caravaca, A.M. Effect of Lactic Acid Bacteria Fermentation on the Polar Compounds Content with Antioxidant and Antidiabetic Activity of Avocado Seed Extracts. Fermentation. 2023, 9(5):  420. https://doi.org/10.3390/fermentation9050420

    Google Scholar 
    [20]    Nallal, V.U.M., Prabha K & Razia, M. Avocado-waste mediated synthesis of Silver nanoparticles and exploration of their potential biological properties. Materials Today: Proceedings. 2022, 64:  1745-1749. https://doi.org/10.1016/j.matpr.2022.05.537

    Google Scholar 
    [21]    Moe, S. & Ngon, E.T. Fatty Acids In Avocado Oil And Nutritional, Antioxidant And Antimicrobial Assessment of The Pulp. Journal of Myanmar Academic Arts and Science.2020, XVIII.(1B): 212-224. 


    [22]    Alkhalaf, M.I., W.S. Alansari, Ibrahim E.A & ELhalwagy, M.E. Anti-oxidant, anti-inflammatory and anti-cancer activities of avocado (Persea americana) fruit and seed extract. Journal of King Saud University-Science. 2019, 31(4):  1358-1362. https://doi.org/10.1016/j.jksus.2018.10.010

    Google Scholar 
    [23]    Ferreira da Vinha, A., J. Moreira &  Barreira,S. Physicochemical parameters, phytochemical composition and antioxidant activity of the algarvian avocado (Persea americana Mill.). Journal of Agricultural Science. 2013, 5(12):  100-109. https://doi.org/10.5539/jas.v5n12p100.

    Google Scholar 
    [24]    Villa-Rodríguez, J.A., F.J. Molina-Corral, J.F. Ayala-Zavala, Olivas G.I & González-Aguilar, G.A. Effect of maturity stage on the content of fatty acids and antioxidant activity of ‘Hass’ avocado. Food Research International. 2011, 44(5):  1231-1237. https://doi.org/10.1016/j.foodres.2010.11.012

    Google Scholar 
    [25]    Abaide, E.R., G.L. Zabot, M.V. Tres, R.F. Martins, J.L. Fagundez, L.F. Nunes, S. Druzian, J.F. Soares, V. Dal Prá & Silva,J.R. Yield, composition, and antioxidant activity of avocado pulp oil extracted by pressurized fluids. Food and Bioproducts Processing. 2017, 102:  289-298. https://doi.org/10.1016/j.fbp.2017.01.008

    Google Scholar 
    [26]    Rotta, E.M., D.R. de Morais, P.B.F. Biondo, V.J. dos Santos, M. Matsushita & Visentainer, J.V. Use of avocado peel (Persea americana) in tea formulation: a functional product containing phenolic compounds with antioxidant activity. Acta Scientiarum. Technology. 2016, 38(1):  23-29. https://doi.org/10.1016/j.fbp.2017.01.008

    Google Scholar 
    [27]    Nabavi, S.F., S.M. Nabavi, W.N. Setzer, S.A. Nabavi, S.A. Nabavi & Ebrahimzadeh, M.A. Antioxidant and antihemolytic activity of lipid-soluble bioactive substances in avocado fruits. Fruits. 2013, 68(3):  185-193. https://doi.org/10.1051/fruits/2013066

    Google Scholar 
    [28]    Abd Elkader, A.M., S. Labib, T.F. Taha, F. Althobaiti, A. Aldhahrani, H.M. Salem, A. Saad & Ibrahim, F.M. Phytogenic compounds from avocado (Persea americana L.) extracts; antioxidant activity, amylase inhibitory activity, therapeutic potential of type 2 diabetes. Saudi journal of biological sciences. 2022, 29(3):  1428-1433. https://doi.org/10.1016/j.sjbs.2021.11.031

    Google Scholar 
    [29]    Corrales-García, J.E., M. del Rosario García-Mateos, E. Martínez-López, A.F. Barrientos-Priego, M.C. Ybarra-Moncada, E. Ibarra-Estrada, Méndez-Zúñiga S.M & D. Becerra-Morales, Anthocyanin and oil contents, fatty acids profiles and antioxidant activity of Mexican landrace avocado fruits. Plant Foods for Human Nutrition. 2019, 74:  210-215. https://doi.org/10.1007/s11130-019-00721-1

    Google Scholar 

    [30]    Terasawa, N., M. Sakakibara & Murata, M. Antioxidative activity of avocado epicarp hot water extract. Food Science and Technology Research. 2006, 12(1):  55-58. https://doi.org/10.3136/fstr.12.55

    Google Scholar 
    [31]    Tahsin, A., R. Arif Muhammed, E. Bayrakdarc & Uthirapathy, S. In-Vitro Antioxidant Activity of Avocado Fruit Oil in Erbil, Kurdistan Region. Eurasian Journal of Science and Engineering. 2023, 8(3): 298-307. https://doi.org/10.23918/eajse.v8i3p298

    Google Scholar 
    [32]    Rozan, M.A., Boriy E.G & Bayomy,HM. Chemical composition, bioactive compounds and antioxidant activity of six avocado cultivars Persea americana Mill.(Lauraceae) grown in Egypt. Emirates Journal of Food and Agriculture. 2021. https://doi.org/10.9755/ejfa.2021.v33.i10.2772

    Google Scholar 
    [33]    Nagaraj, M., V. Sandhya, G. Supriya, R. Manju, K. Pranitha, B. Shivaji,  Lalitha V.L &  Kiran,B.  Antioxidant and antibacterial activity of avocado (Persea gratissima Gaertner.) seed extract. World Applied Sciences Journal. 2010, 9(6):  695-698.

    Google Scholar 
    [34]    Elosaily, A.H., E.A. Mahrous, A.A. Salama, Salama A.M & Elzalabani, S.M. Composition, anti‐inflammatory, and antioxidant activities of avocado oil obtained from Duke and Fuerte cultivars. Journal of the American Oil Chemists' Society. 2022, 99(2):  181-186. https://doi.org/10.1002/aocs.12565

    Google Scholar 
    [35]    Zavala-Guerrero, B., A. Hernandez-Garcia, R. Torres-Martinez, E. Melendez-Herrera, P. Rios-Chavez, A. Ochoa-Zarzosa, J.E. López-Meza, Saavedra-Molina A. & Salgado-Garciglia,R.  Antioxidant and Anti‐inflammatory Activities of Methanolic Fraction from Native Mexican Avocado Seed Oil. The FASEB Journal. 2020, 34(S1):  1-1. https://doi.org/10.1096/fasebj.2020.34.s1.07300.  

    Google Scholar 
    [36]    Hürkul, M.-M., S.-Y. Sarıaltın, Köroğlu A & Çoban, T. In vitro inhibitory potential of avocado fruits, Persea americana (Lauraceae) against oxidation, inflammation and key enzymes linked to skin diseases. Revista de Biología Tropical. 2021, 69(2):  472-481. http://dx.doi.org/10.15517/rbt.v69i2.41494.  

    Google Scholar 
    [37]    Sunday, C.U., H.O. Ndidiamaka, Ugochukwu D.D &. Njideka, I.A. Phytochemical Analysis and Antioxidant Activity of Avocado Pear Peel (Persea americana) Extract. Journal of Pharmaceutical Research International. 2022, 34(28A):  22-29. https://doi.org/10.9734/JPRI/2022/v34i28A36018

    Google Scholar 
    [38]    Ngungeni, Y., J. A. Aboyewa, K.L. Moabelo, N.R. Sibuyi, S. Meyer, M.O. Onani, Meyer M & Madiehe,A.M. Anticancer, Antioxidant, and Catalytic Activities of Green Synthesized Gold Nanoparticles Using Avocado Seed Aqueous Extract. ACS omega. 2023, 8(29):  26088-26101.

    Google Scholar 
    [39]    Charles, A.C., Dadmohammadi Y & A. Abbaspourrad, A. Food and cosmetic applications of the avocado seed: a review. Food & Function. 2022, 13(13):  6894-6901. https://doi.org/10.1039/D1FO02438H.

    Google Scholar 
    [40]    Pușcaș, A., A.E. Tanislav, R.A. Marc, V. Mureșan, A.E. Mureșan,  Pall E & Cerbu, C. Cytotoxicity Evaluation and Antioxidant Activity of a Novel Drink Based on Roasted Avocado Seed Powder. Plants. 2022, 11(8):  1083. https://doi.org/10.3390/plants11081083

    Google Scholar 
    [41]    Aprilianto, E., A.V.H.S. Yuan, Pradita C.D & Hendra, P. Anti-inflammatory effects of avocado peels against inflammation induced by carrageenan in mice. Pharmaciana. 2019, 9(2):  219-226. https://doi.org/10.12928/pharmaciana.v9i2.13607.  

    Google Scholar 
    [42]    Dewi, A., Tianri S.V & Hendra, P.  Anti-inflammatory and analgesic activities of avocado seed (persea americana mill.) aktivitas antiinflamasi dan analgesik biji alpukat (Persea americana mill.) caecilia desi kristanti, fransisca puspa jelita simanjuntak, ni kadek pramita. Jurnal Farmasi Sains dan Komunitas. 2017, 14(2):  104-111. http://dx.doi.org/10.24071/jpsc.142858

    Google Scholar 
    [43]    Dabas, D.,Ziegler G& Lambert, J. Anti-Inflammatory Properties of a Colored Avocado Seed Extract. Advantace Food Technology NutrIitional Sciences. 2019, 5:  8-12. https://doi.org/10.17140/AFTNSOJ-5-151

    Google Scholar 
    [44]    Kristanti, C.D., F.P.J. Simanjuntak, N.K.P.A. Dewi, S.V. Tianri S.V & Hendra, P.  Anti-inflammatory and analgesic activities of avocado seed (Persea americana Mill.). Journal of Pharmaceutical Sciences and Community. 2017, 14(2):  104-111.  https://doi.org/10.24071/jpsc.142858.

    Google Scholar 
    [45]    Ovalle Marín, A., C. Parra Ruiz, F. Rivas Zambrano, J. Orellana, D. García Díaz& P. Jiménez Patiño, Characterization of Persea americana Mill. peels and leaves extracts and analysis of its potential in vitro anti-inflammatory properties. 2020.


    [46]    Oliveira, A.P., E.d.S. Franco, R. Rodrigues Barreto, D.P. Cordeiro, R.G. de Melo, C.M.F. de Aquino, P.L. de Medeiros, T.G. da Silva, Góes A.J &  Maia, MB.Effect of semisolid formulation of Persea americana Mill (avocado) oil on wound healing in rats. Evidence-Based Complementary and Alternative Medicine. 2013, 2013. https://doi.org/10.1155/2013/472382

    Google Scholar 
    [47]    Goudarzi, R., A. Partoazar, F. Mumtaz, H. Yousefi‐Manesh, Abdollahi, A. Dehpour A & Rashidian, A. Arthrocen, an avocado‐soy unsaponifiable agent, improves acetic acid‐induced colitis in rat by inhibition of NF‐kB signaling pathway. Journal of Food Biochemistry. 2020, 44(7):  e13244. https://doi.org/10.1111/jfbc.13244

    Google Scholar 
    [48]    Hasti, S., N. Rahmawati, Utami R & Muharnis, R. Study on Antiinflammatory Effect of N-Hexane And Ethyl Acetate Extract Of Avocado Seed (Persea americana MILL.) on white mice (Mus musculus). Proceeding of “The International Conference on Herbal Medicine Industrialization as Complementary Therapy in Natural Disaster. 2020, 4(2): 42-47. 


    [49]    Soumya, G., 1Akpomie, OO, 1Ehwarieme, DA, O., Ajise, JE, Kovo, GA. Antimicrobial Activity of Persea americana seed extract. Nigerian Journal of Microbiology. 2021.2(1): 45-49. https://doi.org/10.4314/bajopas.v2i1.58538


    [50]    Guzmán-Rodríguez, J.J., R. López-Gómez, L.M. Suárez-Rodríguez, R. Salgado-Garciglia, L.C. Rodríguez-Zapata, A. Ochoa-Zarzosa S.M & . López-Meza, J.E. Antibacterial activity of defensin PaDef from avocado fruit (Persea americana var. drymifolia) expressed in endothelial cells against Escherichia coli and Staphylococcus aureus. BioMed research international. 2013. https://doi.org/10.1155/2013/986273

    Google Scholar 
    [51]    Amado, D.A.V., G.A.B. Helmann, A.M. Detoni, S.L.C.d. Carvalho, C.M.d. Aguiar, C.A. Martin, Tiuman T.S & Cottica, S.M. Antioxidant and antibacterial activity and preliminary toxicity analysis of four varieties of avocado (Persea americana Mill.). Brazilian Journal of Food Technology. 2019, 22. https://doi.org/10.1590/1981-6723.04418

    Google Scholar 
    [52]    Elosaily, A., E.A. Mahrous, Salama A &  Elzalabani, S. Correlation between Genetic Variability, Chemical Composition and Antimicrobial Activity of Essential Oils Isolated from Avocado Cultivars Grown in Egypt. Egyptian Journal of Chemistry. 2021, 64(11):  6155-6159. https://doi.org/10.21608/EJCHEM.2021.71641.3574

    Google Scholar 
    [53]    Salinas‐Salazar, C., C. Hernández‐Brenes, D.G. Rodríguez‐Sánchez, E.C. Castillo, Navarro‐Silva J.M & Pacheco, A.  Inhibitory activity of avocado seed fatty acid derivatives (acetogenins) against Listeria monocytogenes. Journal of Food Science. 2017, 82(1):  134-144.  https://doi.org/10.1111/1750-3841.13553

    Google Scholar 
    [54]    Ilesanmi, T., O. Oladipo, Olaleye A & Osasona, O. Antimicrobial Activity of Essential Oil from Avocado (Persea americana) Seed and Pulp on Some Pathogenic Organisms. South Asian Journal of Research in Microbiology. 2022, 12(3):  61-68. https://doi.org/10.9734/SAJRM/2022/v12i330276

    Google Scholar 
    [55]    Raymond Chia, T.W. & Dykes, G.A. Antimicrobial activity of crude epicarp and seed extracts from mature avocado fruit (Persea americana) of three cultivars. Pharmaceutical Biology. 2010, 48(7):  753-756. https://doi.org/10.3109/13880200903273922

    Google Scholar 
    [56]    Nwaoguikpe, Braide R.W & Ujowundu, C. Biochemical composition and antimicrobial activities of seed extracts of avocado (Persea americana). Journal of Microbiology and Antimicrobials. 2011, 3(7):  184-190.

    Google Scholar 
    [57]    Pacheco, A., D.G. Rodríguez‐Sánchez, R. Villarreal‐Lara, J.M. Navarro‐Silva, Senés‐Guerrero C & Hernández‐Brenes, C. Stability of the antimicrobial activity of acetogenins from avocado seed, under common food processing conditions, against Clostridium sporogenes vegetative cell growth and endospore germination. International journal of food science & technology. 2017, 52(11):  2311-2323. https://doi.org/10.1111/ijfs.13513

    Google Scholar 
    [58]    Gomez-Flores, R., C. Arzate-Quintana, R. Quintanilla-Licea, P. Tamez-Guerra, R. Tamez-Guerra, Monreal-Cuevas E & Rodríguez-Padilla, EC. Antimicrobial activity of Persea americana Mill (Lauraceae)(Avocado) and Gymnosperma glutinosum (Spreng.) Less (Asteraceae) leaf extracts and active fractions against Mycobacterium tuberculosis. American-Eurasian Journal of Scientific Research. 2008, 3(2):  188-194.

    Google Scholar 
    [59]    Leite, J.J.G., É.H.S. Brito, R.A. Cordeiro, R.S.N. Brilhante, J.J.C. Sidrim, L.M. Bertini, Morais S.M.D & Rocha, MFG. Chemical composition, toxicity and larvicidal and antifungal activities of Persea americana (avocado) seed extracts. Revista da Sociedade Brasileira de Medicina Tropical. 2009, 42:  110-113.  https://doi.org/10.1590/S0037-86822009000200003

    Google Scholar 
    [60]    Jesus, D., J. Oliveira, F. Oliveira, K. Higa, J. Junqueira, A. Jorge, Back-Brito G & Oliveira, L. Persea americana glycolic extract: In vitro study of antimicrobial activity against candida albicans biofilm and cytotoxicity evaluation. The Scientific World Journal. 2015, 2015. https://doi.org/10.1155/2015/531972

    Google Scholar 
    [61]    Akalazu, J.N. & Uchegbu, R.I.  Biochemical composition and antimicrobial activities of seed extracts of avocado (Persea americana). The FASEB Journal. 2020, 34(S1):  1-1.

    Google Scholar 
    [62]    Egbuonu, A.C.C., I.C. Opara, Onyeabo C & Uchenna,N.O.  Proximate, functional, antinutrient and antimicrobial properties of avocado pear (Persea americana) Seeds. Journal of Nutritional Health and Food Engineering. 2018, 8(2):  00260. https://doi.org/10.15406/jnhfe.2018.08.00260.

    Google Scholar 
    [63]    Trujillo-Mayol, I., N. Casas-Forero, E. Pastene-Navarrete, Lima Silva F & Alarcón-Enos, J.  Fractionation and hydrolyzation of avocado peel extract: Improvement of antibacterial activity. Antibiotics. 2020, 10(1):  23. https://doi.org/10.3390/antibiotics10010023

    Google Scholar 
    [64]    Hernández-Martínez, M.A., L.M. Suárez-Rodríguez, J.E. López-Meza, A. Ochoa-Zarzosa, R. Salgado-Garciglia, Fernández-Pavia S.P & López-Gómez, R.  Antifungal Activity of Avocado Seed Recombinant GASA/Snakin PaSn. Antibiotics. 2022, 11(11):  1558. https://doi.org/10.3390/antibiotics11111558

    Google Scholar 
    [65]    David, D., A. Alzate, B. Rojano, L. Copete-Pertuz, Jhony Gutierrez R & Zapata-Vahos,I.  Extraction and characterization of phenolic compounds with antioxidant and antimicrobial activity from avocado seed (Persea americana mill). Revis Bionatura 2022; 7 (4): 51-60.

    Google Scholar 
    [66]    Ezati, P., J.-W. Rhim, Molaei R & Rezaei, Z. Carbon quantum dots-based antifungal coating film for active packaging application of avocado. Food Packaging and Shelf Life. 2022, 33:  100878. https://doi.org/10.1016/j.fpsl.2022.100878

    Google Scholar 
    [67]    RajeshKumar, S. & Rinitha, G.  Nanostructural characterization of antimicrobial and antioxidant copper nanoparticles synthesized using novel Persea americana seeds. OpenNano. 2018, 3:  18-27. https://doi.org/10.1016/j.onano.2018.03.001.

    Google Scholar 
    [68]    Villarreal-Lara, R., D.G. Rodríguez-Sánchez, R.I. Díaz De La Garza, M.I. García-Cruz, A. Castillo, Pacheco A & Hernández-Brenes, C.  Purified avocado seed acetogenins: Antimicrobial spectrum and complete inhibition of Listeria monocytogenes in a refrigerated food matrix. CyTA-Journal of Food. 2019, 17(1):  228-239. https://doi.org/10.1080/19476337.2019.1575908

    Google Scholar 
    [69]    Ogunlade, A., U. Azunnaya, Afolabi O & Fakomiti, D. Antimicrobial activity and phytochemical screening of extract of avocado leaf (persea americana) against selected clinical isolates. Using Citrullus colocynthis, Ricinus communis and Parkia biglobosa Seeds. Journal of Science. 2010, 4(2): 12-16. 


    [70]    Pe, N.N., H.H.S. San San Win, N.M. Wai N.M & Mandalay, M. Phytochemical Screening, Antimicrobial Activities and Functional Groups Determination of Isolate Organic Compound from the Barks of Avocado. Journal of Science. 2010, 4(3): 46-51. 


    [71]    Fernández-Castañeda, L.A., H. Arias-Candamil, Zapata-Torres B & Ardila-Castañeda, M.P. Evaluation of the antimicrobial capacity of Hass avocado seed extract (Persea americana) for potential application in the meat industry. Dyna. 2018, 85(207):  346-350. https://doi.org/10.15446/dyna.v85n207.72980.

    Google Scholar 
    [72]    Scarpassa C.,, L. Pretto, G.E. Otaguiri, S. Yamada-Ogatta, G. Nakazato, M. Perugini, Moreira I & Vilas-Bôas, G. Antibacterial activity of avocado extracts (Persea americana Mill.) against Streptococcus agalactiae. Phyton. 2016, 85:  218.

    Google Scholar 
    [73]    Servillon, R.J.T., M.C.C. Dingal, M.C. Lusica, M.K.A. Yamson, Balonebro M.J.B & Alzate, F.B. Phytochemical Screening and in-vitro Antibacterial Evaluation of Persea americana (Avocado) Crude Peel Extract. Optima. 2013, 1(1):  1-1.

    Google Scholar 
    [74]    Makopa, M., B. Mangiza, B. Banda, W. Mozirandi, Mombeshora M & Mukanganyama, S. Antibacterial, antifungal, and antidiabetic effects of leaf extracts from Persea americana Mill.(Lauraceae). Biochemistry Research International. 2020, 2020:  1-10. https://doi.org/10.1155/2020/8884300

    Google Scholar 
    [75]    Bamidele, F., F. Ogundipe, S. Osaide, Chucku G & Olonode, E. Antimicrobial activity and preliminary phytochemical screening of oil extracted from food waste generated from Persea americana. Nigerian Journal of Science and Environment. 2021, 19(2): 17-27. 

    Google Scholar 
    [76]    Kautsar, D.B., M.F. Rois, N. Faizah, W. Widiyastuti, Nurtono T & Setyawan, H. Antioxidant and Antimicrobial Agents from Avocado (Persea Americana) Seed Extract Encapsulated in Gum Arabic through Spray Drying Method. Periodica Polytechnica Chemical Engineering. 2023, 67(1):  161-171. https://doi.org/10.3311/PPch.20698

    Google Scholar 
    [77]    Teresa, R.-C.M., V.-G. Rosaura, Elda C.M & Ernesto,G.P.  The avocado defense compound phenol-2, 4-bis (1, 1-dimethylethyl) is induced by arachidonic acid and acts via the inhibition of hydrogen peroxide production by pathogens. Physiological and molecular plant pathology. 2014, 87:  32-41. https://doi.org/10.1016/j.pmpp.2014.05.003

    Google Scholar 
    [78]    Abdulrahman, M.D. & Hamad, S.W. Traditional methods for treatment and management of measles in Northern Nigeria: Medicinal plants and their molecular docking. Ethnobotany Research and Applications. 2022, 23. http://dx.doi.org/10.32859/era.23.33.1-18

    Google Scholar 
    [79]    Abba, A. & Dogara, A.M.  Ethnomedicinal survey of plants used for management of inflammatory diseases in Ringim local government, Jigawa state, Nigeria. Ethnobotany Research and Applications. 2021, 22:  1-27.

    Google Scholar 
    [80]    Louis, M.L.M., V.P. Rani, P. Krishnan, A.D. Reegan, K. Balakrishna, S. Ignacimuthu, S.M. Packiam,  Maheswaran R & Shirota, O. Mosquito larvicidal activity of compounds from unripe fruit peel of avocado (Persea americana Mill.). Applied Biochemistry and Biotechnology. 2023, 195(4):  2636-2647. https://doi.org/10.1007/s12010-022-03831-w.

    Google Scholar 
    [81]    Al-Otaibi, T., M.A. Hawsah, G. Alojayri, M.M. Mares, H.M. Aljawdah, S.N. Maodaa, E.M. Al-Shaebi, M.A. Dkhil, Thagfan F.A & Al-Quraishy, S. In vivo anticoccidial, antioxidant, and anti-inflammatory activities of avocado fruit, Persea americana (Lauraceae), against Eimeria papillata infection. Parasitology International. 2023, 95:  102741. https://doi.org/10.1016/j.parint.2023.102741

    Google Scholar 
    [82]    Hassan, M., S. Abdel Moneim, Mahmoud E.A.M & Mohamed,D.A.  Antioxidant, anti-Cancer and anti-Arthritic activities of Acetogenin rich extract of Avocado pulp. Egyptian Journal of Chemistry. 2022, 65(2):  539-550. https://doi.org/10.21608/ejchem.2021.90308.4309.

    Google Scholar 
    [83]    Umoh, I., O. Samuel, Kureh T & Davies, K. Antidiabetic and hypolipidaemic potentials of ethanol fruit pulp extract of Persea americana (avocado pear) in rats. Journal of African Association of Physiological Sciences. 2019, 7(1):  59-63.

    Google Scholar 
    [84]    Ojo, O.A., J.C. Amanze, A.I. Oni, S. Grant, M. Iyobhebhe, T.C. Elebiyo, D. Rotimi, N.T. Asogwa, Oyinloye B.E & Ajiboye, B.O. Antidiabetic activity of avocado seeds (Persea americana Mill.) in diabetic rats via activation of PI3K/AKT signaling pathway. Scientific reports. 2022, 12(1):  2919. https://doi.org/10.1038/s41598-022-07015-8

    Google Scholar 
    [85]    Kouamé, N.G.M., C. Koffi, K.S. N’Zoué, N. Yao, B. Doukouré B & Kamagaté, M. Comparative antidiabetic activity of aqueous, ethanol, and methanol leaf extracts of Persea americana and their effectiveness in type 2 diabetic rats. Evidence-Based Complementary and Alternative Medicine. 2019, 2019.

    Google Scholar 
    [86]    Lima, C., C. Vasconcelos, J. Costa-Silva, C. Maranhão, J. Costa, T. Batista, E. Carneiro, L. Soares, Ferreira F & Wanderley, A. Anti-diabetic activity of extract from Persea americana Mill. leaf via the activation of protein kinase B (PKB/Akt) in streptozotocin-induced diabetic rats. Journal of Ethnopharmacology. 2012, 141(1):  517-525.

    Google Scholar 
    [87]    Alhassan, A., M. Sule, M. Atiku, A. Wudil, Abubakar H & Mohammed, S. Effects of aqueous avocado pear (Persea americana) seed extract on alloxan induced diabetes rats. Greener Journal of Medical Sciences. 2012, 2(1):  005-011. https://doi.org/10.15580/GJMS.2012.1.GJMS1202

     



    @article{dogara,abdulrahmanmahmoud2024,
     author = {Dogara, Abdulrahman Mahmoud},
     title = {Biological Activity and Taxonomy of Persea americana Mill: A Systematic Review },
     journal = {Eurasian J. Sci. Eng},
     volume = {10},
     number = {2},
     pages = {46-71},
     year = {2024}
    }
    Copy

    Dogara, A. M. (2024). Biological Activity and Taxonomy of Persea americana Mill: A Systematic Review . Eurasian J. Sci. Eng, 10(2),46-71.

    Copy

    Dogara AM. "Biological Activity and Taxonomy of Persea americana Mill: A Systematic Review ." Eurasian J. Sci. Eng, 10.2, (2024), pp.46-71.

    Copy

    Dogara, A. M. (2024) "Biological Activity and Taxonomy of Persea americana Mill: A Systematic Review ", Eurasian J. Sci. Eng, 10(2), pp.46-71.

    Copy

    Dogara AM. Biological Activity and Taxonomy of Persea americana Mill: A Systematic Review . Eurasian J. Sci. Eng. 2024; 10(2):46-71.

    Copy

    Under Development

    Under Development

    Under Development

  • Biological Activity and Taxonomy of Persea americana Mill: A Systematic Review