Eurasian Journal of Science and Engineering
Volume 8 Issue 3 Article 11
Anti-inflammatory activity of Magic Spice Fruits of Sumac (Rhus coriaria L)
Authors: Saya Mohammed1 & Saran Qasm2 & Zeytun Hameed3 & Parua Walzi4 & Subasini Uthirapathy5
1Faculty of Pharmacy, Tishk International University, Erbil, Kurdistan Region, Iraq
2Faculty of Pharmacy, Tishk International University, Erbil, Kurdistan Region, Iraq
3Faculty of Pharmacy, Tishk International University, Erbil, Kurdistan Region, Iraq
4Faculty of Pharmacy, Tishk International University, Erbil, Kurdistan Region, Iraq
5Faculty of Pharmacy, Tishk International University, Erbil, Kurdistan Region, Iraq
Abstract: The goal of this study is to see how effective Rhus coriaria L (sumac) is at reducing inflammation caused by formalin in mice. The anti-inflammatory efficacy of sumac ethanol extract was tested in mice with formalin-induced paw edema. Anti-inflammatory activity was assessed in mice (n=6) using a plethysmometer model, and it was compared to morphine. Sumac showed anti-inflammatory effects comparable to morphine in mice with formalin-induced paw edema. In a formalin-induced arthritis model, sumac extracts showed considerable anti-inflammatory efficacy. If the findings of this study are supported by more experimental and clinical research, sumac may have an adjuvant role in the treatment of inflammatory illnesses, particularly when antioxidant qualities are present.
Keywords: Formalin Induced Pain, Paw Edema, Sumac, Plethysmometer Model, Rhus Coriaria L
Published: December 22, 2022
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