Quartz Crystal Microbalance a Powerful Technique for Nanogram Mass Sensing

Authors: Sivar Aziz Baiz¹ & Payam Najmaddin² & Azeez A. Barzinjy^3
1Physics Education Department, Faculty of Education, Tishk International University, Erbil, Iraq
²Physics Education Department, Faculty of Education, Tishk International University, Erbil, Iraq
³Physics Education Department, Faculty of Education, Tishk International University, Erbil, Iraq
³Department of Physics, College of Education, Salahaddin University, Erbil, Iraq

Abstract: A quartz crystal microbalance (QCM) is an acoustic transducer that sends an electronic signal when a mass change is detected on the sensor surface of an oscillating quartz-crystal resonator. QCM can detect a small amount of materials in the nanogram range quantitatively from the shift in resonance frequency under vacuum, gas phase, and a liquid environment. QCM is produced by oscillating a piezoelectric, single-crystal quartz plate to measure mass. Quartz’s inherent property of piezoelectricity is the basis of QCM operation. This paper aims to review the role of quartz crystal microbalance in nanotechnology as mass sensing. One of the fundamental driving forces in nanotechnology that positively impact related research areas is new measurement techniques.

Keywords: QCM, Nanotechnology, Piezoelectricity, Resonance Frequency, Mass Sensing, Nanogram

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Doi: 10.23918/eajse.v8i2p1

Published: May 29, 2022

References

Barzinjy, A., Jalal Ismael, H., Abdullah Hamad, M., Mustafa Hamad, S., & Mustafa Ameen, M. (2017). Mathematical modeling of mass change in biosensor quartz crystal microbalance using matlab. Eurasian Journal of Science and Engineering, 3, 204-214.

Abraham, A., Kannangai, R., & Sridharan, G. (2008). Nanotechnology: A new frontier in virus detection in clinical practice. Indian Journal of Medical Microbiology, 26, 297.

Barzinjy, A., & Zankana, M. (2016). A novel application of the quartz crystal microbalance for determining the rheological properties of the highly viscous liquids. Acta Physica Polonica A, 130, 239-244.

Buehler, E., & Walker, A. (1949). Growing quartz crystals. The Scientific Monthly, 69, 148-155.

Cheng, C. I., Chang, Y. P., & Chu, Y. H. (2012). Biomolecular interactions and tools for their recognition: focus on the quartz crystal microbalance and its diverse surface chemistries and applications. Chemical Society Reviews, 41, 1947-1971.

Curie, J., & Curie, P. (1880). Piezoelectric and allied phenomena in Rochelle salt. Comput Rend Acad Sci Paris, 91, 294-297.

Daikhin, L., Gileadi, E., Katz, G., Tsionsky, V., Urbakh, M., & Zagidulin, D. (2002). Influence of roughness on the admittance of the quartz crystal microbalance immersed in liquids. Analytical Chemistry, 74, 554-561.

Dirri, F., Palomba, E., Longobardo, A., Zampetti, E., Saggin, B., & Scaccabarozzi, D. (2019). A review of quartz crystal microbalances for space applications. Sensors and Actuators A: Physical, 287, 48-75.

Elam, J., Groner, M., & George, S. (2002). Viscous flow reactor with quartz crystal microbalance for thin film growth by atomic layer deposition. Review of Scientific Instruments, 73, 2981-2987.

Ferreira, G. N., Da-Silva, A. C., & Tomé, B. (2009). Acoustic wave biosensors: physical models and biological applications of quartz crystal microbalance. Trends in Biotechnology, 27, 689-697.

Jain, K. K. (2005). Nanotechnology in clinical laboratory diagnostics. Clinica Chimica Acta, 358, 37-54.

Johannsmann, D. (2014). The quartz crystal microbalance in soft matter research: Fundamentals and modeling, Springer International Publishing.

Johannsmann, D., Langhoff, A., & Leppin, C. (2021). Studying soft interfaces with shear waves: Principles and applications of the quartz crystal microbalance (QCM). Sensors, 21, 3490.

Kanazawa, K., & Cho, N. J. (2009). Quartz crystal microbalance as a sensor to characterize macromolecular assembly dynamics. Journal of Sensors, 2009.

Kanazawa, K. K., & Gordon, J. G. (1985). The oscillation frequency of a quartz resonator in contact with liquid. Analytica Chimica Acta, 175, 99-105.

Kankare, J. (2002). Sauerbrey equation of quartz crystal microbalance in liquid medium. Langmuir, 18, 7092-7094.

Khanna, V. K. (2016). Nanosensors: Physical, chemical, and biological, CRC Press.

Lehmann, G., & Bambauer, H. U. (1973). Quartz crystals and their colors. Angewandte Chemie International Edition in English, 12, 283-291.

Lin, Z., & Ward, M. D. (1996). Determination of contact angles and surface tensions with the quartz crystal microbalance. Analytical Chemistry, 68, 1285-1291.

Liu, G., Wu, Z., & Craig, V. S. (2008). Cleaning of protein-coated surfaces using nanobubbles: An investigation using a quartz crystal microbalance. The Journal of Physical Chemistry C, 112, 16748-16753.

Marx, K. A. (2003). Quartz crystal microbalance: A useful tool for studying thin polymer films and complex biomolecular systems at the solution-surface interface. Biomacromolecules, 4, 1099-1120.

Nilebäck, E., Feuz, L., Uddenberg, H., Valiokas, R., & Svedhem, S. (2011). Characterization and application of a surface modification designed for QCM-D studies of biotinylated biomolecules. Biosensors and Bioelectronics, 28, 407-413.

Rehman, A., & Zeng, X. (2015). Methods and approaches of utilizing ionic liquids as gas sensing materials. RSC Advances, 5, 58371-58392.

Reviakine, I., Johannsmann, D., & Richter, R. P. (2011). Hearing what you cannot see and visualizing what you hear: interpreting quartz crystal microbalance data from solvated interfaces. ACS Publications.

Roy, J., Laughton, C., & Allen, S. (2010). Quartz crystal microbalance (QCM) studies for the investigation of ligand (IBM) interactions with major urinary protein (MUP). Journal of Pharmacy and Pharmacology, 1370-1371.

Santos, L. M., Lima, L. M. S. S., Lima, C. F., Magalhães, F. D., Torres, M. C., Schröder, B., & Da Silva, M. A. R. (2011). New Knudsen effusion apparatus with simultaneous gravimetric and quartz crystal microbalance mass loss detection. The Journal of Chemical Thermodynamics, 43, 834-843.

Sauerbrey, G. (1959). Use of vibrating quartz for thin film weighing and microweighing. Z. Phys, 155, 206-222.

Tan, F., Qiu, D. Y., Guo, L. P., Ye, P., Zeng, H., Jiang, J., Tang, Y., & Zhang, Y. C. (2016). Separate density and viscosity measurements of unknown liquid using quartz crystal microbalance. Aip Advances, 6(9), 095313.

Villaverde, A. (2011). Nanoparticles in translational science and medicine, Academic Press.

Vogt, B. D., Lin, E. K., Wu, W. L., & White, C. C. (2004). Effect of film thickness on the validity of the Sauerbrey equation for hydrated polyelectrolyte films. The Journal of Physical Chemistry B, 108, 12685-12690.

Zhang, X., Chen, J., Liu, H., & Zhang, S. (2015). Quartz crystal microbalance detection of protein amplified by nicked circling, rolling circle amplification and biocatalytic precipitation. Biosensors and Bioelectronics, 65, 341-345.

Ward, M. D., & Buttry, D. A. (1990). In situ interfacial mass detection with piezoelectric transducers. Science, 249, 1000-1007.