Characterization of Chemical Compounds in Volatile Oil and Ethyl Acetate Extract of Lavandula angustifolia by GC-MS

Authors: Javed Ahamad¹ & Duran Kala² & Esra T. Anwer³ & Subasini Uthirapathy^4
1Department of Pharmacognosy, Faculty of Pharmacy, Tishk International University, Erbil, Iraq
²Department of Biology Education, Faculty of Education, Tishk International University, Erbil, Iraq
³Department of Pharmaceutics, Faculty of Pharmacy, Tishk International University, Erbil, Iraq
⁴Department of Pharmacology, Faculty of Pharmacy, Tishk International University, Erbil, Iraq

Abstract: Lavandula angustifolia is an important aromatic plant and rich source of linalool. L. angustifolia and its bioactive compounds have been reported to possess several bioactivities such as antioxidant, antifungal, antibacterial and antidiabetic etc. The aim of the present study is to characterize chemical compounds present in volatile oil and ethyl acetate extract of L. angustifolia aerial parts by gas chromatography mass spectroscopy (GC-MS). The hydrodistillation of aerial parts of L. angustifolia yielded 1.56±0.27% v/w volatile oil. The GC-MS analysis of volatile oil of L. angustifolia yielded 74 chemical compounds, and lavandulyl isobutyrate (52.61%), and linalool (5.41%) were identified as major compounds. Ultrasonication was utilized for extraction of L. angustifolia using ethyl acetate as solvent and extraction yield was found to be 3.59±0.73% w/w. The GC-MS analysis of ethyl acetate extract of L. angustifolia yielded 40 chemical compounds and the major compounds were dotriacontane (8.33%), linalool (7.09%), eucalyptol (6.42%), linalyl acetate (4.69%), 1,4-cineole (4.62%), and trans-linalool oxide (4.51%). The present study explores the chemical composition of volatile oil and ethyl acetate extract of L. angustifolia.

Keywords: Lavandula angustifolia, Lamiaceae, GC-MS, Linalool, Aromatic Plant, Hydrodistillation, Ultrasonication

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Doi: 10.23918/eajse.v7i2p10

Published: December 16, 2021

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